Clinical Research

Clinical research is fundamental to Sonex Health’s mission to deliver physicians innovative therapies that reduce invasiveness, improve safety, and reduce the cost of care.

Ultrasound-Guided Carpal Tunnel Release

Ultrasound-guided carpal tunnel release (UGCTR) was initially described by Nakamichi in 1997.10, 11 Since then, over 30 peer reviewed publications have reported clinical results on over 3,000 hands (>2,500 patients) treated with UGCTR. 7, 11-22 The collective clinical success rate is over 95%, with these publications documenting the safety and effectiveness of UGCTR, an excellent safety profile, and the ability to perform the procedure in the in the clinic setting.7, 11-22

Clinical Experience

The first ultrasound-guided carpal tunnel release using UltraGuideCTRTM was performed in February 2017.


  • Over 43,000 procedures completed including many simultaneous bilateral releases12-22

  • Procedures performed in the ASC, OR and clinic setting – most procedures performed using only local anesthesia/WALANT technique12-15, 17, 19-22

  • Post-operative discomfort typically managed with acetaminophen or NSAIDs as necessary12, 13-15, 17-22

  • Statistically and clinically significant improvements in patient-reported outcome measures as early as 1-2 weeks and sustained at up to 6 years post-procedure12, 13, 15, 16, 18, 19, 21, 22

  • Most patients can return to work in 3-5 days12, 16, 19, 20
UltraGuideCTR under real-time ultrasound showing carpal tunnel anatomy

Ultrasound-Guided Carpal Tunnel Release with UltraGuideCTR™:
Clinical Summary